Pemphigus vulgaris mimicking Steven-Johnson syndrome/toxic epidermal necrolysis: report of an unusual case

Pemphigus vulgaris (PV) is an autoimmune blistering disease affecting the skin and mucosa. It clinically presents as painful erosions, mainly in oral cavity, flaccid blisters erosions on skin. Steven-johnson syndrome/toxic epidermal necrolysis (SJS/TEN) a severe mucocutaneous drug hypersensitivity reaction characterized by painful, dusky, erythematous eruptions that often progress to blisters, extensive detachment accompanied systemic symptoms. Herein, we report case of 48-year-old man who presented with mucosal lesions following ingestion unknown medication. The patient’s symptoms thus mimicked SJS accordingly, preliminary diagnosis was made. Clinical investigation biopsy direct immunofluorescence assay results, however, indicated PV final established.